STUDY SHOWS EARLY BRAIN CHANGES PREDICT
WHICH PATIENTS DEVELOP CHRONIC PAIN
www.telegraph.co.uk
- Emotions may determine why some people are more likely to
suffer chronic pain than others, a study has found. The emotional state
of the brain can explain why different individuals do not respond the
same way to similar injuries, say scientists. Some recover fully while
others remain in constant pain. Brain scan studies showed for the first
time how chronic pain emerges as a result of an emotional response to an
injury. The process involves interaction between two brain regions, the
frontal cortex and nucleus accumbens.
Lead
scientist Professor Vania Apakarian, from Northwestern University in
Chicago, US, said: ''The injury itself is not enough to explain the
ongoing pain. It has to do with the injury combined with the state of
the brain.'' The more emotionally the brain reacted to the initial
injury, the more likely it was that pain will persist after the injury
has healed, he said. The finding provides a new direction for
developing therapies to treat intractable pain. Prof Apakarian added:
''It may be that these sections of the brain are more excited to begin
with in certain individuals, or there may be genetic and environmental
influences that predispose these brain regions to interact at an
excitable level.''
"For
the first time, we can explain why people who may have the exact same
initial pain either go on to recover or develop chronic pain," explain
Prof Apakarian. The research involved 40 volunteers who had all suffered
an episode of back pain lasting one to four months. Four brain scans
were carried out on each participant over the course of one year. The
results, published in the journal Nature Neuroscience, made it possible
to predict with 85% accuracy which individuals would go on to develop
chronic pain. The nucleus accumbens teaches the rest of the brain how to
evaluate and react to the outside world.
Prof
Apakarian said it may use the initial pain signal to teach other parts
of the brain to develop chronic pain. ''Now we hope to develop new
therapies for treatment based on this finding,'' he added. An estimated
30 million to 40 million U.S. adults suffer from chronic pain. Back pain
is the most prevalent chronic pain condition. "Chronic pain is one of
the most expensive health care conditions in the U.S., yet there still
is not a scientifically validated therapy for this condition," Apkarian
said. Chronic pain costs an estimated $600 billion a year, according to a
2011 National Academy of Sciences report.
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When
people have similar injuries, why do some end up with chronic pain
while others recover and are pain free? A new study finds that the
brain's emotional reaction to the injury is crucial to either lead to
recover or develop chronic pain. Emotions are a key factor in
determining how a person reacts and feels while he is in pain. The more
emotionally the brain reacts to the initial injury, the more likely the
pain will persist after the injury has healed. Unless we reach the
spiritual platform, we experience both bodily pleasure and pain on this
material platform.
WHAT DO THE VEDIC TEACHINGS TELL US?
In
the Bhagavad-gita Arjuna's mind was disturbed due to being attached to
sense objects in the form of his relatives. ... Because the self is the
witness of the many changes of the mind, such as happiness and distress,
it must be different from them and changeless, for an entity subject to
change cannot be a witness of that change. As the self is different
from the gross body, so too is it different from the subtle body, which
consists of various states of the fluctuating mind. The experience of
happiness and distress differs from that of heat and cold inasmuch as
heat and cold can be either enjoyable or distressful, whereas happiness
and distress remain the same. ... All of these experiences are relative
to the mind's wedding with the senses and their apprehension of sense
objects. That which is at one time hot may be cold at another. That
which brings happiness may later be the cause of distress. These mental
perceptions create a world in which the self lives without knowledge of
itself, in the world of the mind. The first step out of this small world
is theoretical knowledge followed by tolerance.
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